2009
Depp and Heard first met on the set of the film "The Rum Diary" in 2009.
Based on Hunter S. Thompson's book of the same name, the movie stars Depp as a journalist named Paul Kemp who takes a job in Puerto Rico. Heard played Chenault, who Kemp falls for at first sight.
On the witness stand in the defamation trial, Depp described the connection he felt with Heard when a scene called for their characters to kiss in a shower.
"That moment, was, it was, it felt like something, it felt like something I should not be feeling," Depp said, explaining they were each in other relationships at the time. "I think there was something in the kiss in the shower that was real."
Depp testified the two next saw each other two years later on a promotional tour for the film.
2012
Depp and his longtime partner Vanessa Paradis, who share two children, Lily-Rose and John Christopher, parted ways in 2012.
Heard and Depp began dating and later got engaged in 2014, according to a report by People magazine at the time.
2016
Heard filed for divorce after 15 months of marriage. She obtained a temporary restraining order against Depp, claiming he abused her while under the influence of drugs and alcohol.
2018
Heard penned a op-ed for The Washington Post in December of 2018 about the treatment of women in domestic abuse cases. She did not mention Depp by name.
2019
Depp sued Heard for $50 million for defamation over her Washington Post piece, claiming it cost him lucrative acting work.
Heard was unsuccessful in her effort to get the lawsuit dismissed. Her $100 million countersuit case is ongoing.
2020
In 2020, Depp brought the publisher of The Sun to court for libel in the UK over a 2018 article that claimed he was violent against Heard.
Johnny Depp during his libel case in London in 2020.
Depp denied all claims of abuse.
Heard testified in that case, claiming at one point that Depp threatened to kill her "many times."
The UK court found the paper's claims to be "substantially true," and Depp was denied an appeal.
2022
The trial for Depp's defamation case against Heard began in Virginia on April 12.
Heard's lawyer said in an opening statement that Depp is "going to try to turn this case into a soap opera."
Depp has testified about his experiences growing up with an abusive mother, his struggles with substance abuse and his tumultuous relationship with Heard.
Depp acknowledged in his testimony that he and Heard had arguments during their relationship but said, "Never did I myself reach the point of striking Ms. Heard in any way nor have I ever struck any woman in my life."
At the conclusion of his testimony this week he was questioned by his attorney, Jessica Meyers, about a piece of audio that was played for the court.