High-performance CPU/GPU computing complex design and development with hybrid CPU/GPU architecture: - design of message-passing and event driven architecture - design of high throughput multithreaded cooperation principles of calculations on CPU and GPU - design of numerical task forming, description, transactional storage and run-time decomposition approaches for load balancing on distributed nodes with different latency, reliability and performance - design of server-side and management panels GUI interfaces - design and forming of UML data model description - database management (PostgreSQL)